Table 1.

IC50 of sunitinib for different tyrosine kinase receptors

RTK	Cellular IC50 (μM)
FLT3	0.25
KIT	0.022
RET	0.1
PDGFR α/β	0.002
VEGFR1	0.002
VEGFR2	0.07
VEGFR3	0.017

Abbreviations: FLT3, fetal liver tyrosine kinase receptor 3; IC50, half maximal inhibitory concentration; PDGFR, platelet-derived growth factor receptor; VEGFR, vascular endothelial growth factor receptor.