Table 2.
Distribution of phthalate metabolite concentrations at 13 and 26 weeks gestation.
| Exposure * | 13 Weeks (N = 432) | 26 Weeks (N = 417) | Correlation | p-Value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Median | IQR | 5th | 95th | Median | IQR | 5th | 95th | |||
| MEP | 161.8 | (67.3, 435.1) | 24.3 | 1618.6 | 153.3 | (65.6, 376.3) | 22.2 | 1262.1 | 0.389 | 4.44 × 10−16 |
| MBP | 18.4 | (9.1, 37.9) | 3.7 | 102.4 | 22.6 | (11.7, 42.6) | 5.0 | 121.6 | 0.211 | 1.76 × 10−5 |
| MiBP | 2.4 | (1.1, 4.5) | 0.2 | 14.0 | 2.8 | (1.4, 5.2) | 0.4 | 14.4 | 0.267 | 4.46 × 10−8 |
| ΣLMW | 211.9 | (100.7, 524.4) | 40.0 | 1806.8 | 217.8 | (113.7, 451.4) | 43.2 | 1506.3 | 0.371 | 9.77 × 10−15 |
| MEHP | 3.0 | (1.4, 6.4) | 0.2 | 17.7 | 3.6 | (1.9, 6.7) | 0.4 | 18.0 | 0.199 | 5.04 × 10−5 |
| MEHHP | 12.6 | (6.8, 24.7) | 2.5 | 76.9 | 15.7 | (8.3, 28.1) | 3.3 | 66.2 | 0.233 | 2.02 × 10−6 |
| MEOHP | 8.7 | (4.7, 16.7) | 1.6 | 47.2 | 12.1 | (6.8, 21.1) | 2.8 | 48.4 | 0.204 | 3.37 × 10−5 |
| MECPP | 22.0 | (13.7, 39.7) | 5.9 | 104.0 | 25.8 | (16, 45.6) | 8.5 | 97.5 | 0.241 | 8.79 × 10−7 |
| ΣDEHP | 46.0 | (27.6, 84.3) | 11.8 | 242.3 | 57.8 | (33.2, 99.3) | 16.1 | 235.5 | 0.231 | 2.35 × 10−6 |
| MBzP | 6.6 | (3.1, 12.7) | 0.9 | 32.1 | 7.6 | (4.3, 14) | 1.5 | 38.1 | 0.378 | 2.66 × 10−15 |
| MCPP | 1.8 | (1, 2.9) | 0.1 | 6.4 | 2.1 | (1.2, 3.2) | 0.2 | 6.4 | 0.154 | 1.76 × 10−3 |
| MCOP | 2.8 | (1.7, 4.6) | 0.5 | 10.7 | 3.2 | (2.1, 5) | 0.8 | 9.6 | 0.138 | 5.30 × 10−3 |
| MCNP | 1.8 | (1, 2.7) | 0.4 | 7.2 | 1.9 | (1.3, 2.8) | 0.6 | 5.8 | 0.206 | 2.80 × 10−5 |
| ΣHMW | 65.7 | (37.8, 110.4) | 17.6 | 303.8 | 79.5 | (46.8, 126.4) | 24.2 | 270.5 | 0.244 | 6.37 × 10−7 |
| Isoprostane ** | 3.6 | (2.2, 5.0) | 1.0 | 10.8 | 4.6 | (3.1, 6) | 1.2 | 8.9 | 0.176 | 3.34 × 10−2 |
* All units are µg/g creatinine; ** N = 166 for 13 weeks and N = 180 for 26 weeks.