Table 3.
Regression models of phthalate metabolite concentrations with isoprostane levels at 13 and 26 weeks gestation a.
Phthalate Metabolite (µg/g Creatinine) | 13 Weeks (n = 166) | 26 Weeks (n = 180) | Change (n = 150) | ||||||
---|---|---|---|---|---|---|---|---|---|
β | 95% CI | p-Value | β | 95% CI | p-Value | β | 95% CI | p-Value | |
MEP | 0.045 | (−0.031, 0.121) | 0.2486 | 0.074 | (0.003, 0.145) | 0.0417 | 0.110 | (0.014, 0.206) | 0.0271 |
MBP | 0.064 | (−0.028, 0.156) | 0.1721 | 0.183 | (0.083, 0.283) | 0.0004 | 0.094 | (−0.006, 0.194) | 0.0684 |
MiBP | −0.002 | (−0.088, 0.084) | 0.9665 | 0.097 | (0.023, 0.171) | 0.0108 | 0.059 | (-0.031, 0.149) | 0.2012 |
ΣLMW | 0.056 | (−0.028, 0.140) | 0.2007 | 0.109 | (0.029, 0.189) | 0.0087 | 0.144 | (0.036, 0.252) | 0.0099 |
MEHP | 0.006 | (−0.080, 0.092) | 0.8949 | 0.057 | (−0.023, 0.137) | 0.1643 | 0.073 | (−0.019, 0.165) | 0.1239 |
MEHHP | 0.066 | (−0.048, 0.180) | 0.2526 | 0.068 | (−0.018, 0.154) | 0.1271 | 0.101 | (-0.009, 0.211) | 0.0768 |
MEOHP | 0.064 | (−0.036, 0.164) | 0.2160 | 0.072 | (−0.018, 0.162) | 0.1220 | 0.092 | (-0.014, 0.198) | 0.0910 |
MECPP | 0.087 | (−0.050, 0.224) | 0.2151 | 0.074 | (−0.040, 0.188) | 0.2002 | 0.130 | (−0.005, 0.265) | 0.0613 |
ΣDEHP | 0.075 | (−0.052, 0.202) | 0.2499 | 0.080 | (−0.026, 0.186) | 0.1349 | 0.131 | (0.004, 0.258) | 0.0464 |
MBzP | 0.045 | (−0.059, 0.149) | 0.3983 | 0.012 | (−0.074, 0.098) | 0.7805 | 0.076 | (−0.032, 0.184) | 0.1710 |
MCPP | 0.033 | (−0.045, 0.111) | 0.4142 | 0.125 | (0.035, 0.215) | 0.0072 | 0.003 | (−0.052, 0.112) | 0.4728 |
MCOP | 0.178 | (0.062, 0.294) | 0.0031 | 0.090 | (−0.020, 0.200) | 0.1119 | 0.078 | (−0.045, 0.201) | 0.2188 |
MCNP | 0.152 | (0.029, 0.275) | 0.0166 | 0.136 | (0.021, 0.250) | 0.0211 | 0.110 | (−0.014, 0.233) | 0.0832 |
ΣHMW | 0.088 | (−0.050, 0.226) | 0.2119 | 0.092 | (−0.026, 0.209) | 0.1300 | 0.142 | (0.002, 0.283) | 0.0487 |
a Covariates in each regression model included creatinine and categorical variables for years in U.S., education level, parity, pre−pregnancy BMI and sex of child.