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. 2016 Dec 20;6:39630. doi: 10.1038/srep39630

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Correlation analysis of PRKAR1A level and CDH1 mRNA in TCGA dataset of 522 lung adenocarcinoma patients (r = 0.1285, P = 0.0033). (B) Correlation analysis of PRKAR1A level and CDH1 mRNA in 102 lung adenocarcinoma patients from XiangYa Hospital lung tumor tissue bank who underwent surgical resection (r = 0.3814, P < 0.0001). (C) Representative images of immunohistochemical staining for PRKAR1A and E-cadherin in human adenocarcinoma tissues.