Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Dec 20;6:39377. doi: 10.1038/srep39377

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

The levels of several inflammatory and ischemia-related factors were measured via a multiplex assay. (A) Inflammatory chemokines. RANTES levels were significantly increased, whereas eotaxin levels did not change in the placenta 3 days after coil stenosis. (B) Inflammatory cytokines. Cytokine levels did not significantly change in the placenta following mild intrauterine hypoperfusion (MIUH) on E17, although all inflammatory cytokines showed increasing trends. n = 11 in the control group and n = 12 in the MIUH group. (C) Ischemia-related proteins. The levels of vWF, VEGF, and adiponectin were significantly increased in the placenta following MIUH. n = 13 in the control group and n = 14 in the MIUH group. ^*P < 0.05, vs. the control group. (D) mRNA expression levels of an immature neuron maker (nestin), axonal makers (APP and GAP43), astrocyte makers (GFAP and S100β), and oligodendrocyte makers (PDGFRα and NG2) in the whole brain (n = 5 in each group). β-actin was used as an internal control for gene expression. The mRNA expression levels of APP, GAP-43 and GFAP in brains on E20 were significantly decreased following MIUH. ^*P < 0.05, ^**P < 0.01 vs. the control group. E, Embryonic day.