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. 2016 Dec 20;6:39477. doi: 10.1038/srep39477

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Copyright © 2016, The Author(s)

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(a) Schematic describling a strategy of preparation the SF/SA scaffolds. (b) EDC reaction mechanism schematic with SA and SF: (1) reaction with amino groups, (2) reaction with a nearby ionized carboxyl group and (3) quickly form amide bond when amine is present.