Table 2. Heritability estimates of various structural measures of subcortical brain regions.

Region	Gross volume		Radial distance		Jacobian determinant		PCA radial distance		PCA Jacobian determinant
	h2	P	h2*	P	h2*	P	h2*	P	h2*	P
Left hemisphere
Amygdala	8.1	0.18	47.7	1.72 × 10−6	35.4	2.85 × 10−4	29.9	4.40 × 10−4	27.9	9.30 × 10−4
Accumbens	11.6	0.099	34.0	4.71 × 10−4	33.7	5.11 × 10−4	28.7	7.04 × 10−4	42.0	1.45 × 10−6
Caudate	33.7	8.6 × 10−5	49.9	6.33 × 10−7	52.9	1.40 × 10−7	42.4	1.20 × 10−6	35.1	4.73 × 10−5
Hippocampus	10.8	0.12	32.7	7.32 × 10−4	29.2	2.23 × 10−3	28.9	6.59 × 10−4	29.6	5.03 × 10−4
Pallidum	32.2	1.7 × 10−4	39.6	5.75 × 10−5	44.1	8.65 × 10−6	30.8	2.96 × 10−4	27.0	1.33 × 10−3
Putamen	43.4	6.8 × 10−7	49.4	7.43 × 10−7	52.7	1.45 × 10−7	34.1	7.16 × 10−5	40.7	2.92 × 10−6
Thalamus	34.1	7.4 × 10−5	53.3	1.05 × 10−7	45.3	5.07 × 10−6	30.2	3.78 × 10−4	29.4	5.26 × 10−4
Right hemisphere
Amygdala	20.4	0.012	33.5	5.45 × 10−4	31.5	1.08 × 10−3	30.5	3.45 × 10−4	27.7	1.03 × 10−3
Accumbens	1.6	0.43	33.1	6.30 × 10−4	35.1	3.13 × 10−4	34.5	5.99 × 10−5	31.7	2.10 × 10−4
Caudate	34.7	5.4 × 10−5	46.7	2.86 × 10−6	47.5	1.95 × 10−6	29.9	4.45 × 10−4	33.8	8.75 × 10−5
Hippocampus	8.0	0.19	33.7	5.26 × 10−4	17.7	4.23 × 10−2	30.8	3.00 × 10−4	28.9	6.44 × 10−4
Pallidum	36.6	2.3 × 10−5	46.4	3.12 × 10−6	44.5	7.22 × 10−6	41.4	1.97 × 10−6	29.2	5.77 × 10−4
Putamen	37.1	1.8 × 10−5	42.6	1.70 × 10−5	37.5	1.32 × 10−4	32.7	1.36 × 10−4	33.4	1.01 × 10−4
Thalamus	30.8	3.0 × 10−4	46.2	3.50 × 10−6	50.4	4.50 × 10−7	37.1	1.78 × 10−5	31.8	2.02 × 10−4

h², heritability estimate in %; PCA, principal component analysis.

^*Estimate indicates highest heritability among all vertices or principal components.