Table 2.

Summary of average response magnitudes and frequencies for each peptide spanning Cryj 1, Cry j 2 and Cryj IFR for each donor cohort.

			Average response magnitude (SFC)						Average response frequency (%)
Peptide start	Antigen	Sequence	LIJ IgE+	SD	NLJ IgE+	St. Dev	LIJ IgE−	SD	LIJ IgE+	NLJ IgE+	LIJ IgE−
1	Cry j 1	MDSPCLVALLVFSFVI	30	68	3	17	0	0	20	4	0
9	Cry j 1	LLVFSFVIGSCFSDNP	9	28	4	19	0	0	10	4	0
17	Cry j 1	GSCFSDNPIDSCWRGD	110	349	0	0	0	0	10	0	0
25	Cry j 1	IDSCWRGDSNWAQNRM	147	466	0	0	29	129	10	0	5
33	Cry j 1	SNWAQNRMKLADCAVG	97	308	0	0	29	90	10	0	10
41	Cry j 1	KLADCAVGFGSSTMGG	39	122	7	35	93	404	20	4	10
49	Cry j 1	FGSSTMGGKGGDLYTV	18	58	0	0	0	0	10	0	0
57	Cry j 1	KGGDLYTVTNSDDDPV	64	203	8	41	0	0	10	4	0
65	Cry j 1	TNSDDDPVNPAPGTLR	16	50	0	0	6	28	10	0	5
73	Cry j 1	NPAPGTLRYGATRDRP	384	928	0	0	0	0	20	0	0
81	Cry j 1	YGATRDRPLWIIFSGN	72	141	3	15	0	0	30	4	0
89	Cry j 1	LWIIFSGNMNIKLKMP	401	490	4	18	54	200	70	4	10
97	Cry j 1	MNIKLKMPMYIAGYKT	153	322	91	444	0	0	20	4	0
105	Cry j 1	MYIAGYKTFDGRGAQV	210	448	8	30	0	0	30	9	0
113	Cry j 1	FDGRGAQVYIGNGGPC	218	280	8	37	54	199	60	4	10
121	Cry j 1	YIGNGGPCVFIKRVSN	231	438	22	75	90	251	30	9	15
129	Cry j 1	VFIKRVSNVIIHGLYL	363	495	45	146	3	13	60	17	5
137	Cry j 1	VIIHGLYLYGCSTSVL	29	65	0	0	0	0	20	0	0
145	Cry j 1	YGCSTSVLGNVLINES	0	0	0	0	0	0	0	0	0
153	Cry j 1	GNVLINESFGVEPVHP	67	130	0	0	0	0	30	0	0
161	Cry j 1	FGVEPVHPQDGDALTL	172	368	0	0	0	0	20	0	0
169	Cry j 1	QDGDALTLRTATNIWI	54	134	0	0	63	176	30	0	15
177	Cry j 1	RTATNIWIDHNSFSNS	543	832	121	593	53	175	50	4	10
185	Cry j 1	DHNSFSNSSDGLVDVT	82	150	15	74	0	0	40	4	0
193	Cry j 1	SDGLVDVTLTSTGVTI	77	167	3	15	0	0	30	4	0
201	Cry j 1	LTSTGVTISNNLFFNH	13	40	0	0	0	0	10	0	0
209	Cry j 1	SNNLFFNHHKVMLLGH	414	852	16	45	18	60	30	13	10
217	Cry j 1	HKVMLLGHDDAYSDDK	0	0	0	0	0	0	0	0	0
225	Cry j 1	DDAYSDDKSMKVTVAF	298	796	3	14	16	71	30	4	5
233	Cry j 1	SMKVTVAFNQFGPNCG	369	634	108	315	19	57	40	26	10
241	Cry j 1	NQFGPNCGQRMPRARY	0	0	0	0	14	60	0	0	5
249	Cry j 1	QRMPRARYGLVHVANN	157	441	124	440	14	62	20	9	5
257	Cry j 1	GLVHVANNNYDPWTIY	238	524	49	239	18	81	30	4	5
265	Cry j 1	NYDPWTIYAIGGSSNP	64	202	0	0	0	0	10	0	0
273	Cry j 1	AIGGSSNPTILSEGNS	8	25	0	0	15	67	10	0	5
281	Cry j 1	TILSEGNSFTAPNESY	722	963	22	106	24	107	60	4	5
289	Cry j 1	FTAPNESYKKQVTIRI	127	332	0	0	0	0	20	0	0
297	Cry j 1	KKQVTIRIGCKTSSSC	27	58	0	0	34	134	20	0	10
305	Cry j 1	GCKTSSSCSNWVWQST	0	0	0	0	0	0	0	0	0
313	Cry j 1	SNWVWQSTQDVFYNGA	579	746	0	0	35	115	60	0	10
321	Cry j 1	QDVFYNGAYFVSSGKY	254	348	12	46	47	151	40	9	10
329	Cry j 1	YFVSSGKYEGGNIYTK	152	394	15	61	8	34	20	9	5
337	Cry j 1	EGGNIYTKKEAFNVEN	132	185	3	14	12	52	40	4	5
345	Cry j 1	KEAFNVENGNATPQLT	140	253	4	20	0	0	40	4	0
353	Cry j 1	GNATPQLTKNAGVLTC	144	222	72	290	9	38	40	17	5
359	Cry j 1	LTKNAGVLTCSLSKRC	118	228	13	65	18	78	20	4	5
1	Cry j 2	MAMKLIAPMAFLAMQL	8	24	8	37	0	0	0	4	0
9	Cry j 2	MAFLAMQLIIMAAAED	19	60	0	0	0	0	10	0	0
17	Cry j 2	IIMAAAEDQSAQIMLD	9	28	0	0	0	0	0	0	0
25	Cry j 2	QSAQIMLDSWEKYLR	26	62	3	16	0	0	20	4	0
33	Cry j 2	SVVEKYLRSNRSLRKV	0	0	7	25	0	0	0	9	0
41	Cry j 2	SNRSLRKVEHSRHDAI	11	36	6	27	0	0	10	4	0
49	Cry j 2	EHSRHDAINIFNVEKY	0	0	0	0	0	0	0	0	0
57	Cry j 2	NIFNVEKYGAVGDGKH	28	61	9	29	0	0	20	9	0
65	Cry j 2	GAVGDGKHDCTEAFST	0	0	3	12	0	0	0	4	0
73	Cry j 2	DCTEAFSTAWQAACKN	450	787	2	12	0	0	40	4	0
81	Cry j 2	AWQAACKNPSAMLLVP	391	783	2	12	0	0	30	4	0
89	Cry j 2	PSAMLLVPGSKKFVVN	340	946	30	102	0	0	30	13	0
97	Cry j 2	GSKKFWNNLFFNGPC	295	809	157	656	24	107	30	17	5
105	Cry j 2	NLFFNGPCQPHFTFKV	20	62	89	413	0	0	10	9	0
113	Cry j 2	QPHFTFKVDGIIAAYQ	760	785	49	201	136	351	60	13	20
121	Cry j 2	DGIIAAYQNPASWKNN	888	840	114	358	226	549	70	22	25
129	Cry j 2	NPASWKNNRIWLQFAK	216	400	20	79	24	66	50	9	15
137	Cry j 2	RIWLQFAKLTGFTLMG	246	597	62	196	112	345	50	17	15
145	Cry j 2	LTGFTLMGKGVIDGQG	14	44	6	20	14	46	10	9	10
153	Cry j 2	KGVIDGQGKQWWAGQC	29	91	0	0	0	0	10	0	0
161	Cry j 2	KQWWAGQCKWVNGREI	18	58	5	26	0	0	10	4	0
169	Cry j 2	KWVNGREICNDRDRPT	118	333	13	61	3	11	30	4	5
177	Cry j 2	CNDRDRPTAIKFDFST	41	88	18	71	20	62	20	9	10
185	Cry j 2	AIKFDFSTGLIIQGLK	187	442	15	63	140	416	40	9	25
193	Cry j 2	GLIIQGLKLMNSPEFH	47	69	7	35	9	42	40	4	5
201	Cry j 2	LMNSPEFHLVFGNCEG	77	160	5	26	14	47	30	4	10
209	Cry j 2	LVFGNCEGVKIIGISI	225	628	0	0	4	16	40	0	5
217	Cry j 2	VKIIGISITAPRDSPN	384	686	70	273	192	459	60	13	25
225	Cry j 2	TAPRDSPNTDGIDIFA	9	30	0	0	2	10	10	0	5
233	Cry j 2	TDGIDIFASKNFHLQK	33	78	9	46	16	70	20	4	5
241	Cry j 2	SKNFHLQKNTIGTGDD	176	329	0	0	9	40	30	0	5
249	Cry j 2	NTIGTGDDCVAIGTGS	113	357	13	61	0	0	10	4	0
257	Cry j 2	CVAIGTGSSNIVIEDL	146	461	12	59	5	22	10	4	5
265	Cry j 2	SNIVIEDLICGPGHGI	166	468	3	13	4	17	30	4	5
273	Cry j 2	ICGPGHGISIGSLGRE	0	0	5	18	16	53	0	9	10
281	Cry j 2	SIGSLGRENSRAEVSY	104	147	23	112	25	64	50	4	15
289	Cry j 2	NSRAEVSYVHVNGAKF	363	548	0	0	33	108	50	0	15
297	Cry j 2	VHVNGAKFIDTQNGLR	130	234	0	0	10	32	40	0	10
305	Cry j 2	IDTQNGLRIKTWQGGS	0	0	0	0	0	0	0	0	0
313	Cry j 2	IKTWQGGSGMASHIIY	0	0	0	0	0	0	0	0	0
321	Cry j 2	GMASHIIYENVEMINS	50	158	0	0	0	0	10	0	0
329	Cry j 2	ENVEMINSENPILINQ	6	19	2	10	0	0	10	4	0
337	Cry j 2	ENPILINQFYCTSASA	115	329	0	0	11	35	20	0	10
345	Cry j 2	FYCTSASACQNQRSAV	26	81	0	0	9	38	10	0	5
353	Cry j 2	CQNQRSAVQIQDVTYK	86	237	0	0	8	34	20	0	5
361	Cry j 2	QIQDVTYKNIRGTSAT	474	693	2	10	95	306	50	4	15
369	Cry j 2	NIRGTSATAAAIQLKC	298	650	7	24	24	78	30	9	10
377	Cry j 2	AAAIQLKCSDSMPCKD	70	148	0	0	15	48	30	0	10
385	Cry j 2	SDSMPCKDIKLSDISL	19	61	0	0	0	0	10	0	0
393	Cry j 2	IKLSDISLKLTSGKIA	602	848	7	26	17	56	60	9	10
401	Cry j 2	KLTSGKIASCLNDNAN	809	832	21	103	28	78	70	4	15
409	Cry j 2	SCLNDNANGYFSGHVI	49	156	0	0	0	0	10	0	0
417	Cry j 2	GYFSGHVIPACKNLSP	0	0	0	0	9	39	0	0	5
425	Cry j 2	PACKNLSPSAKRKESK	99	262	0	0	0	0	20	0	0
433	Cry j 2	SAKRKESKSHKHPKTV	0	0	0	0	0	0	0	0	0
441	Cry j 2	SHKHPKTVMVENMRAY	0	0	2	11	0	0	0	4	0
449	Cry j 2	MVENMRAYDKGNRTRI	0	0	4	18	0	0	0	4	0
457	Cry j 2	DKGNRTRILLGSRPPN	24	76	14	71	0	0	10	4	0
465	Cry j 2	LLGSRPPNCTNKCHGC	0	0	0	0	0	0	0	0	0
473	Cry j 2	CTNKCHGCSPCKAKLV	0	0	0	0	0	0	0	0	0
481	Cry j 2	SPCKAKLVIVHRIMPQ	0	0	5	27	0	0	0	4	0
489	Cry j 2	IVHRIMPQEYYPQRWI	0	0	0	0	0	0	0	0	0
497	Cry j 2	EYYPQRWICSCHGKIY	7	21	13	65	0	0	10	4	0
499	Cry j 2	YPQRWICSCHGKIYHP	63	199	14	47	0	0	10	9	0
1	Cry j IFR	MGGSRVLIIGGTGYIG	0	0	4	19	0	0	0	4	0
9	Cry j IFR	IGGTGYIGRHVTNASL	0	0	0	0	0	0	0	0	0
17	Cry j IFR	RHVTNASLAQGHPTFL	0	0	0	0	0	0	0	0	0
25	Cry j IFR	AQGHPTFLLVREITPS	0	0	0	0	0	0	0	0	0
33	Cry j IFR	LVREITPSNPEKAQLL	0	0	0	0	0	0	0	0	0
41	Cry j IFR	NPEKAQLLESFTSKGA	0	0	0	0	0	0	0	0	0
49	Cry j IFR	ESFTSKGATLVQGSID	0	0	0	0	0	0	0	0	0
57	Cry j IFR	TLVQGSIDDHASLVAA	0	0	0	0	0	0	0	0	0
65	Cry j IFR	DHASLVAALKKVDVVI	0	0	0	0	0	0	0	0	0
73	Cry j IFR	LKKVDWISTLGAPQI	0	0	0	0	0	0	0	0	0
81	Cry j IFR	STLGAPQIADQFNLIK	0	0	0	0	0	0	0	0	0
89	Cry j IFR	ADQFNLIKAIKEVGTI	0	0	14	49	0	0	0	9	0
97	Cry j IFR	AIKEVGTIKRFFPSEF	0	0	18	61	0	0	0	9	0
105	Cry j IFR	KRFFPSEFGNDVDKHH	0	0	10	36	0	0	0	9	0
113	Cry j IFR	GNDVDKHHAVEPMKSM	0	0	22	67	0	0	0	13	0
121	Cry j IFR	AVEPMKSMFDLKIKLR	0	0	26	66	0	0	0	17	0
129	Cry j IFR	FDLKIKLRRTIEAEGI	0	0	11	53	0	0	0	4	0
137	Cry j IFR	RTIEAEGIPHTYWPH	0	0	0	0	0	0	0	0	0
145	Cry j IFR	PHTYVVPHCFAGYFLT	0	0	14	52	0	0	0	9	0
153	Cry j IFR	CFAGYFLTNLAQLGLA	0	0	8	38	0	0	0	4	0
161	Cry j IFR	NLAQLGLAAPPRDKIV	0	0	3	15	0	0	0	4	0
169	Cry j IFR	APPRDKIVIYGDGTTK	0	0	0	0	3	13	0	0	5
177	Cry j IFR	IYGDGTTKAVYMKEED	0	0	0	0	0	0	0	4	0
185	Cry j IFR	AVYMKEEDIGTFTIKA	0	0	3	12	0	0	0	4	0
193	Cry j IFR	IGTFTIKAVDDPRTLN	0	0	3	14	0	0	0	4	0
201	Cry j IFR	VDDPRTLNKTLYLKPP	0	0	4	19	0	0	0	4	0
209	Cry j IFR	KTLYLKPPANTISTND	0	0	0	0	0	0	0	0	0
217	Cry j IFR	ANTISTNDLVALWEAK	0	0	0	0	0	0	0	0	0
225	Cry j IFR	LVALWEAKIGKTLEKV	0	0	0	0	0	0	0	0	0
233	Cry j IFR	IGKTLEKVYLSEEQVL	0	0	0	0	0	0	0	0	0
241	Cry j IFR	YLSEEQVLKLLQDTPF	0	0	0	0	0	0	0	0	0
249	Cry j IFR	KLLQDTPFPGTFMVSI	0	0	0	0	0	0	0	0	0
257	Cry j IFR	PGTFMVSIFHTIYVKG	0	0	0	0	5	20	0	0	5
265	Cry j IFR	FHTIYVKGDQTNFQIG	0	0	0	0	0	0	0	0	0
273	Cry j IFR	DQTNFQIGPDGVEASA	0	0	0	0	0	0	0	0	0
281	Cry j IFR	PDGVEASALYPDVKYT	0	0	0	0	0	0	0	0	0
289	Cry j IFR	LYPDVKYTTVEEYISA	0	0	8	39	26	74	0	4	15
291	Cry j IFR	PDVKYTTVEEYISAFV	0	0	0	0	8	34	0	0	5

SD- standard deviation