Table 3.
Predictors of CD4 counts in separate multivariable models for HIV-uninfected and infected women in Uganda and Zimbabwe
Variable | HIV uninfected (n = 208)
|
HIV infected (n = 180*)
|
||||
---|---|---|---|---|---|---|
Estimated CD4 | 95% CI | P value† | Estimated CD4 | 95% CI | P value† | |
Intercept | 927 | 774, 1080 | <0.001 | 658 | 547, 770 | <0.001 |
Country | ||||||
Zimbabwe | −114 | −206, −23 | 0.014 | −202 | −287, −117 | <0.001 |
Uganda | Reference | Reference | ||||
Majority contraceptive use‡§ | ||||||
COC | −27 | −126, 71 | 0.590 | 131 | 21, 240 | 0.019 |
DMPA | −38 | −138, 62 | 0.454 | 20 | −65, 105 | 0.649 |
NH | Reference | Reference | ||||
Age (years)§ | ||||||
18–24 | 27 | −82, 135 | 0.629 | 34 | −64, 133 | 0.496 |
25–29 | 50 | −42, 141 | 0.287 | −1 | −79, 77 | 0.980 |
30 and up | Reference | Reference | ||||
≤9 years of education** | 39 | −51, 129 | 0.395 | −19 | −93, 54 | 0.608 |
Living with partner†† | 39 | −87, 165 | 0.544 | 9 | −69, 87 | 0.817 |
Currently pregnant§ | – | – | – | −154 | −294, −14 | 0.031 |
Eight women were excluded in the HIV-infected model due to missing data
Based on chi-square test by the generalized estimating equation model with Gamma distribution
Combined oral contraceptive (COC), depot-medroxyprogesterone acetate (DMPA) and non-hormonal (NH) contraceptive methods
At CD4 study visit, which occurred between July 2003 and January 2004 for the HIV-uninfected group and between March 2001 and July 2007 for the HIV-infected group
At Hormonal Contraception and Risk of HIV Acquisition (HC–HIV) screening visit (13–45 months prior to the CD4 visit)
At HC–HIV screening visit (13–45 months prior to the CD4 visit) for the HIV-uninfected group; at GS enrolment visit (0–6 months prior to the CD4 visit) for the HIV-infected group