Table 5. Sensitivity and specificity of AFP according to concomitant albumin levels and NA therapy.
Group | 1 | 2 | 3 | 4 |
---|---|---|---|---|
NA (-) Albumin ≥ 3.7 | NA (+) Albumin ≥ 3.7 | NA (-) Albumin < 3.7 | NA (+) Albumin < 3.7 | |
Number (HCC-associated) | 20,702 (105) | 29,330 (234) | 685 (37) | 2,420 (73) |
Youden index | 0.646 | 0.497 | 0.369 | 0.215 |
Cutoff (ng/mL) | 3.9 | 5.3 | 25.0 | 67.2 |
Sensitivity | 80 | 65 | 49 | 33 |
Specificity | 85 | 85 | 87 | 89 |