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. 2016 Mar 27;7(27):40953–40964. doi: 10.18632/oncotarget.8397

Figure 3. PILRα-Ig binds some CD56 bright NK clones and causes IFNγ secretion.

Figure 3

A., B. FACS staining of isolated CD56bright, CD16negative, CD3negative NK clones. Grey filled histograms are background control staining. Black line histograms represent specific staining, as indicated. (A) PILRα-Ig positive NK clone. (B) PILRα-Ig negative clone. C., D. IFNγ secretion by PILRα-Ig positive NK clones (C) and by PILRα-Ig negative NK clones (D) following incubation with 721.221 cells transfected either with an empty vector as control, or with PILRα. Figure combine 3 independent experiments. *p < 0.05, NS-not significant. Statistics was performed using student T-test.