Table 2. Genetic variants of HOTAIR and EOC risk.
| Genotype | Cases | Controls | Adjusted OR (95% CI)* |
|---|---|---|---|
| rs4759314 | |||
| AA | 819 | 852 | 1.00 (reference) |
| AG | 140 | 125 | 1.16 (0.90–1.51) |
| GG | 41 | 23 | 1.85 (1.11–3.09) |
| G vs A | 1.34 (1.08–1.65) | ||
| P trend | 6.8 × 10−3 | ||
| rs7958904 | |||
| GG | 594 | 533 | 1.00 (reference) |
| CG | 355 | 380 | 0.84 (0.70–1.01) |
| CC | 51 | 87 | 0.53 (0.37–0.75) |
| C vs G | 0.77 (0.67–0.89) | ||
| P trend | 4.2 × 10−4 | ||
| rs874945 | |||
| GG | 665 | 677 | 1.00 (reference) |
| AG | 283 | 279 | 1.03 (0.85–1.26) |
| AA | 52 | 44 | 1.20 (0.79–1.82) |
| A vs G | 1.07 (0.91–1.25) | ||
| P trend | 0.382 | ||
*
Asjusting for age at diagnosis, family history of cancer, smoking status, drinking status, and BMI.