Table 1. Results of radiographic analyses to determine disease progression.
| ID | Exam | Response category | Criteria used | Findings |
|---|---|---|---|---|
| 1 | CT without IV contrast | Progressive Disease (PD) | RECIST 1.1 | Progression based on non-target disease (lung nodules) |
| 2 | CT with IV contrast | Progressive Disease (PD) | RECIST 1.1 | Progression based on new bony lytic lesions |
| 3 | CT with IV contrast | Progressive Disease (PD) | RECIST 1.1 | Unequivocal progression based on numerous new lesions, new lymphangitic spread, worsened pleural effusion |
| 4 | PET | Progressive Disease (PD) | PERCIST | Progression based on development of new lesion |
| 5 | CT without IV contrast | Progressive Disease (PD) | RECIST 1.1 | Progression based on development of new lesions and increase in size of several non-target lesions |
| 6 | CT with IV contrast and MRI with IV contrast for brain | Progressive Disease (PD) | RECIST 1.1 | Progression based on development of new brain metastasis |
| 7 | CT without IV contrast | Progressive Disease (PD) | RECIST 1.1 | Progression based on increase in size of target lesions |
| 8 | CT without IV contrast | Progressive Disease (PD) | RECIST 1.1 | Progression based on new bony lytic lesion |
| 9 | CT without IV contrast | Progressive Disease (PD) | RECIST 1.1 | Progression based on development of numerous new lesions |
Abbreviations: RESIST = Response Evaluation Criteria in Solid Tumors.
PERCIST = PET Response Criteria in Solid Tumors.