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. 2016 May 13;7(27):41662–41676. doi: 10.18632/oncotarget.9340

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Copyright: © 2016 Liguori et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Immunofluorescence of TRAIL-R2 and TRAIL-R3 and leukocyte markers. A-B. Sections of un-diseased human spleen and lung; C-D. Sections of human mammary, hepatic and colon carcinoma. Macrophages (CD68), T cells (CD3) and granulocytes (myeloperoxidase) are marked in green, TRAIL-R2 and R3 in red and nuclei in blue. Macrophages from tumor tissues, but not from normal tissues, express TRAIL-R2 and do not express TRAIL-R3.