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Glucocorticoids (10−7M, 24 hrs) induce up-regulation of TRAIL-R1-2 in monocytes while IL-10 (25 ng/ml, 24 hrs) induces up-regulation of TRAIL-R1-2 and to a lesser extent of TRAIL-R3 in monocytes (A) and macrophages (B). Results are shown as fold increase relative to untreated cells (mean ± SE of 3 different experiments). Statistical analysis: *P < 0.05, ** P < 0.01, *** P < 0.001 (Student's t test).
