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. 2016 May 20;7(27):41677–41690. doi: 10.18632/oncotarget.9528

Figure 1. Study design.

Figure 1

Blood was collected at the time of disease progression (TP0) and at two consecutive clinical staging time points (TP1 and TP2). Patients were stratified according to response to therapy into Responder/Non-Responder at TP1 and in Overall-Responder (OR; Response at TP1 and TP2) and Overall-Non-Responder (ONR; No response at TP1 and TP2), as well as Late Responder (LR; No response at TP1, response at TP2) and Late Non-Responder (LNR; Response at TP1, no response at TP2) at TP2.