Table 2. Genes associated with reduced OS at TP1.

Gene expression in Non-Responders at TP1	p-value	Hazard ratio	95% CI of ratio
ERCC1	0,0031	0.04723	0.006212 to 0.3591
EGFR	0,0084	0.01274	0.0004959 to 0.3274
ERCC1 + ERBB2	0,0293	0.4091	0.1590 to 0.6592
ERCC1 + ERBB3	0,0084	0.2727	0.06499 to 0.4805
ERCC1 + AURKA	0,0094	0.3636	0.1135 to 0.6137
EGFR + AURKA	0,0084	0.2727	0.06499 to 0.04805
EGFR + ERBB3	0,0084	0.2727	0.06499 to 0.04805

The genes and gene combinations listed were significantly associated with a shorter OS. For Responders, no significant single gene or combinations could be identified.