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. 2016 May 21;7(27):41691–41702. doi: 10.18632/oncotarget.9541

Table 3. Characteristics of non-small cell lung cancer patients with MET exon 14 skipping.

Cases Sex Age Smoking P. T. Subtype Stage MET IHC EGFR CN HER2 CN TTF1
1 F 67 Never A 3.5 Acinar IB ++ > 8 > 6
2 F 77 Never A 2 Lepidic+Acinar IB + > 4 2 +
3 M 66 Smoker A 4 Papillary IIA ++ > 4 2 +
4 F 74 Never A 2.3 Lepidic IA ++ > 6 2 +
5 F 54 Never A 2 Acinar+Papillary IB ++ > 10 2
6 M 60 Smoker A 4.5 Solid IB ++ > 7 2 +
7 F 75 Never A 2.5 Solid IB +++ > 5 2 +
8 F 60 Never A 4 Acinar+Lepidic IIB + > 8 2 +
9 F 62 Never A 3 Acinar+Solid IA ++ > 5 2 +
10 F 49 Never A 1 AAH 0 2 2 +
11 F 60 Never A 2.8 Lepidic IA + 2 4 +
12 F 75 Never A 2.5 IMA+Acinar IA + > 5 2
13 M 76 Never A 0.5 Acinar IA ++ > 5 > 5 +
14 M 76 Smoker A 2.8 Lepidic+Acinar IA > 5 3 +
15 M 67 Never A 1.5 AIS 0 2 2 +
16 F 57 Never A 0.8 AIS 0 + 2 2 +
17 F 73 Never A 4 Papillary IIA + 2 2 +
18 F 47 Never A 0.9 AIS 0 2 2 +
19 F 63 Never A 2 Papillary+Micropapillary IIA + > 7 2 +
20 M 68 Smoker A 3.2 Solid IIA ++ > 8 > 3 +
21 M 68 Never A 3.5 Acinar+Solid IIIA +++ > 5 3 +
22 M 65 Smoker AS 10 N.A. IIB + > 4 2 +
23 F 77 Never AS 1.5 N.A. IA + > 5 > 4 +

Abbreviations: F, female, M, male; P, pathology; T. tumor size (cm); AAH, atypical adenomatous hyperplasia; AIS, adenocarcinoma in situ; IHC, MET immunohistochemistry; EGFR CN, EGFR gene copy by EGFR-FISH analysis; HER2 CN, HER2 gene copy by HER2-FISH analysis; N.A., not available; AAH, Atypical adenomatous hyperplasia; AIS, adenocarcinoma in situ (AIS).