Table 2. Univariate and multivariate Cox regression analyses of GAPLINC expression and clinical variables for overall survival of patients with CRC.

Variables	Categories	Univariate analysis			Multivariate analysis
		HR	95% CI	P value	HR	95% CI	P value
Age (year)	>60/≤60	1.514	0.869–2.637	0.143
Sex	Maleemale	0.974	0.642–1.475	0.905
Size (cm)	≥5/<5	1.519	1.002–2.303	0.045*	1.156	0.728–1.834	0.539
T stage	1/2/3/4	2.153	1.534–3.021	<0.01**	1.222	0.668–2.233	0.516
N stage	N0/N1/N2	2.144	1.615–2.846	<0.01**	1.528	0.900–2.595	0.116
Grade	I/II/III	2.789	1.575–4.940	<0.01**	1.972	1.197–3.250	<0.01**
GAPLINC	High / low	2.730	1.771–4.207	<0.01**	2.214	1.375–3.565	<0.01**

Abbreviations: HR, hazard ratio; 95% CI, 95% confidence interval.

^*Statistically significant (P < 0.05).