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. 2016 May 31;7(27):42195–42207. doi: 10.18632/oncotarget.9743

Figure 2. Synergistic anti-tumor effects of the combination of HVJ-E and poly I:C.

Figure 2

A. The combination of HVJ-E (2500 HAU) and poly I:C (25 μg) was more effective for tumor suppression than a double dose of HVJ-E (5000 HAU) or poly I:C (50 μg) (n=6). * Indicates p<0.05. B. Elispot assay for splenocytes. Splenocytes were isolated from tumor-bearing mice that were treated with 3 injections of PBS, poly I:C (25 μg), HVJ-E (2500 HAU) or HVJ-E+poly I:C (H+P) (25 μg+2500 HAU) 10 days after the last treatment (n=4). The numbers of IFN-γ-positive splenocytes stimulated with B16-F10 cells were counted. * Indicates p<0.05. NS indicates not significant.