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. 2016 May 31;7(27):42195–42207. doi: 10.18632/oncotarget.9743

Figure 7. Combination of HVJ-E and poly I:C induced neutrophil-mediated anti-tumor effects in MC38 and 4T1 tumor models.

Figure 7

Mouse colon adenocarcinoma MC38 A. and mouse mammary carcinoma 4T1 B. cells were transplanted to C57BL/6 and Balb/c mice, respectively. On day 4 after tumor cell inoculation, tumors were treated with HVJ-E (2500 HAU) combined with poly I:C (25 μg) or PBS. For neutrophil depletion, the Ly6G (1A8) antibody or isotype control antibody was injected intraperitoneally (100 μg) three times 24 hours before HVJ-E+poly I:C treatment and once 24 hours after the last treatment (total of four times). * Indicates p<0.05.