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A. pY36-specific phosphorylation signal was enhanced by the ERα/ERβ common agonist 17-β-estradiol and two ERβ-specific agonists DPN and S-equol in MDA-MB-231 cells. B. S-equol treatment inhibited MDA-MB-231 cell-derived xenograft tumor growth (n = 5). C. Expression of Ki-67 in xenograft tumors. D. ERβ-pY36 signal in vehicle- and S-equol-treated xenograft tumor samples.* p<0.05, **p<0.01.
