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. Author manuscript; available in PMC: 2016 Dec 20.
Published in final edited form as: Pac Symp Biocomput. 2016;22:485–496. doi: 10.1142/9789813207813_0045

Fig. 4. Model Predictions.

Fig. 4

(A) Pathways with increased activity in brain tumors. Metabolites are glucose (GLC), fructose-6-phosphate (F6P), acetyl-CoA (ACoA), glutamine (GLN), glutamate (GLU), glucosamine-6-phosphate (GA6P), Uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), oxoglutarate (OXO), beta-alanine (ALAB), and malonate semialdehyde (MSA). (B) Relative protein expression and sampled flux values for proteins differentially expressed between AML and ALL pediatric patients. ODC1 participates in the reaction Ornithine Decarboxylase (ORNDC), and PIK3CA participates in reactions PI4P3K, PI45P3K, PI5P3K, and PIK3. All reactions are labeled as in the BiGG database.65