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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Immunol. 2016 Nov 28;198(1):352–362. doi: 10.4049/jimmunol.1600914

Figure 1. T. gondii causes myositis and skeletal muscle damage.

Figure 1

(A) C57BL/6 mice were orally infected with 5 ME49 T. gondii cysts. Body weight was monitored for up to 35 dpi. (B) Representative images of H&E stained skeletal muscle sections from naïve and infected (30 dpi.) mice. (C) Blinded histopathological scoring of muscle damage and inflammation naïve and infected (12 and 30 dpi.) skeletal muscle. (D) Functional muscle strength was quantified in naïve and infected (>30 dpi.) mice by measuring hang time on Kondziela's inverted screen test. ***P< 0.001, Student's t test (A-D) Results are representative of at least two experiments with n = 4 mice per group/experiment; error bars are the SD.