Table 5: Key eligibility criteria for reimbursement of paritaprevir-ritonavir-ombitasvir plus dasabuvir (with or without ribavirin) for treatment of hepatitis C virus infection, by jurisdiction.
| Jurisdiction | Restriction | ||||
|---|---|---|---|---|---|
| Minimum fibrosis stage required | Substance use | HIV coinfection | Prescriber | Decompensated cirrhosis | |
| Province/territory | |||||
| British Columbia | F2 | None listed* | Eligible | General practitioner | None listed |
| Alberta | F2 | None listed | Eligible | General practitioner | Ineligible |
| Saskatchewan | F2 | None listed† | Eligible | General practitioner | Ineligible |
| Manitoba | F2 | None listed | Eligible | Specialist | Ineligible |
| Ontario | F2 | None listed | Eligible | General practitioner | Ineligible |
| Quebec | F3‡ | None listed | Eligible§ | General practitioner | Ineligible |
| New Brunswick | F2 | None listed | Eligible | General practitioner | Ineligible |
| Nova Scotia | F2 | None listed | Eligible | Specialist | Ineligible |
| Prince Edward Island | No restrictions | None listed¶ | Eligible** | General practitioner | None listed |
| Newfoundland and Labrador | F2 | None listed | Eligible | General practitioner | Ineligible |
| Yukon | F2 | None listed | Eligible | Specialist | Ineligible |
| Northwest Territories | F2 | None listed | None listed | None listed | None listed |
| Nunavut | F2 | None listed | None listed | None listed | None listed |
| Federal | |||||
| Non-Insured Health Benefits Program | F2 | None listed | None listed | None listed | None listed |
| Correctional Service Canada | F2†† | None listed | None listed | None listed | None listed |
*No specific criteria, but exclusion criteria stated: "Patients who are at high risk for non-compliance."
†However, prescriber could indicate that directly observed therapy was recommended; also, the patient consented (via signature) to understanding treatment adherence.
‡In year 1 (2015/16), only those with stage F3 or F4 fibrosis received reimbursement.
§Treated in year 1 if stage F3 or F4 fibrosis.
¶There were restrictions (e.g., active injection drug use) left to physician's discretion.
**Must be treated by a specialist off-island.
††Treatment prioritized to patients with stage F3 or F4 fibrosis; treatment for those with stage F0, F1 or F2 fibrosis was reviewed on a case-by-case basis.