Table 2.
Time | Number of studies | Total number of patients | Hedges’s g (CI) | p Value | NNT (CI) |
---|---|---|---|---|---|
Less than 4 weeks | 8 | 578 | 0.44 (0.15–0.73) | 0.003 | NA |
4–8 weeks | 11 | 691 | 0.52 (0.27–0. 78) | < 0.001 | 4.9 (3.3 −9.5) |
8–12 weeks | 8 | 564 | 0.23 (−0.09 to 0. 56) | 0.162 | NA |
NNT = number needed to treat; NA = not applicable owing to either minimal control event rate (less than 0.1%) or nonsignificant results.