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. 2016 Jul 28;475(1):232–243. doi: 10.1007/s11999-016-5002-1

Table 2.

Pooled standardized mean difference of pain reduction for corticosteroid injection versus placebo injection

Time Number of studies Total number of patients Hedges’s g (CI) p Value NNT (CI)
Less than 4 weeks 8 578 0.44 (0.15–0.73) 0.003 NA
4–8 weeks 11 691 0.52 (0.27–0. 78) < 0.001 4.9 (3.3 −9.5)
8–12 weeks 8 564 0.23 (−0.09 to 0. 56) 0.162 NA

NNT = number needed to treat; NA = not applicable owing to either minimal control event rate (less than 0.1%) or nonsignificant results.