Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proposed model illustrating the mechanisms of inhibition activity of GSE on HCV replication and HCV-induced inflammation response. GSE suppresses HCV replication by down-regulating the COX-2 expression through reducing the NF-κB and MAPK/ERK/JNK signaling pathways. Moreover, GSE significantly reduced the virus-induced inflammation response upon HCV infection or oncogenic viral protein overexpression.
