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. 2016 Oct 20;34(1):136–147. doi: 10.1007/s11095-016-2049-3

Fig. 3.

Fig. 3

Effect of PPI-m DS G4 dendrimers on nuclear translocation of NF-κB in THP-1 cells. Subcellular localisation of NF-κB was determined by high-content screening (immunofluorescence with anti-p65 antibody and automated microscopy/image analysis) after 2.5 h of treatment with dendrimers. Treatment with 100 ng/ml TNFα was used as positive control of NF-κB nuclear translocation. Data presented as percentage of nuclear to cytoplasmic staining ratio in control (untreated) cells, average ± S.E.M., n = 6.