Table 1.
Neuronal and synaptic model parameters
| Parameter Description | Parameter Symbol | Parameter Value |
|---|---|---|
| Na conductance, PY neurons | GNaPY | 10 mS/cm2 |
| K conductance, PY neurons | GKPY | 10 mS/cm2 |
| Leak conductance, PY neurons | GLPY | 1.2 ± 0.1 mS/cm2 |
| Adaptation conductance, PY neurons | GAPY | 3 mS/cm2 |
| Na conductance, FS neurons | GNaFS | 35 mS/cm2 |
| K conductance, FS neurons | GKFS | 9 mS/cm2 |
| Leak conductance, FS neurons | GLFS | 0.1 ± 0.05 mS/cm2 |
| Capacitance (PY and FS neurons) | Cm | 1 μF/cm2 |
| Peak AMPA conductance, PY to PY | g̃AMPAPY←PY | 0.12 mS/cm2 |
| Peak AMPA conductance, PY to FS | g̃AMPAFS←PY | 0.02 mS/cm2 |
| Peak GABA conductance, FS to PY, ipsilateral | g̃GABAPY←FS | 5 mS/cm2 |
| Peak GABA conductance, FS to FS, ipsilateral | g̃GABAFS←FS | 0.003 mS/cm2 |
| Peak GABA conductance, FS to PY, contralateral | g̃GABAPY←FS | 1.25 mS/cm2 |
| Peak GABA conductance, FS to FS, contralateral | g̃GABAFS←FS | 0.00075 mS/cm2 |
| Peak NMDA conductance, PY to PY | g̃NMDAPY←PY | 0.048 mS/cm2 |
| Peak NMDA conductance, PY to FS | g̃NMDAFS←PY | 0.001 mS/cm2 |
| Peak GABA conductance, callosal FS to PY | g̃GABA,CCPY←FS | 1.25 mS/cm2 |
| Peak GABA conductance, callosal FS to FS | g̃GABA,CCFS←FS | 0.00075 mS/cm2 |
| AMPA decay time, PY to PY | τAMPAPY←PY | 5.0 ms |
| NMDA decay time, PY to PY | τNMDAPY←PY | 100.0 ms |
| GABA decay time, FS to PY | τGABAPY←FS | 10.0 ms |
| AMPA decay time, PY to FS | τAMPAFS←PY | 2.0 ms |
| NMDA decay time, PY to FS | τNMDAFS←PY | 50 ms |
| GABA decay time, FS to FS | τGABAFS←FS | 10.0 ms |
| Recovery time, Glu synapse | τR,Glu | 800.0 ms |
| Recovery time, GABA synapse | τR,GABA | 400.0 ms |
| Synaptic depression, Glu synapse | uGlu | 0.5 |
| Synaptic depression, GABA synapse | uGABA | 0.2 |
| Canonic AMPA/NMDA conductance, PY neurons | GPY | 130.0 mS/cm2 |
| Canonic AMPA/NMDA conductance, FS neurons | GFS | 10.0 mS/cm2 |
FS, fast spiking; PY, pyramidal.