TABLE 1.
Comparison of abilities of E. coli and A. actinomycetemcomitans LPS to upregulate CD86 expression by immature DCsa
| Amt (ng) of LPS | Mean fluorescence intensityb
|
P value | |
|---|---|---|---|
| E. coli | A. actinomycetemcomitans | ||
| 0.1 | 94 ± 0.2 | 131 ± 2.7 | <0.01 |
| 1 | 133 ± 3.5 | 147 ± 6.3 | <0.03 |
| 10 | 129 ± 6.3 | 151 ± 7.3 | <0.02 |
a
Monocytes were cultured with GM-CSF and IL-4 for 5 days, and then various concentrations of LPS from E. coli or A. actinomycetemcomitans were added for 1 day.
b
The background fluorescence intensity for CD86 on DCs in the absence of any LPS was 102 ± 6.4. Data are means ± SE.