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. 2004 Sep;72(9):4956–4965. doi: 10.1128/IAI.72.9.4956-4965.2004

FIG. 2.

FIG. 2.

Histopathology of tibiotarsal joints from control and RB6-treated mice. Representative sections were obtained from a control IgG-treated C3H mouse (A) and an RB6-treated mouse (B to G) sacrificed 7 days postinfection. (A and B) H&E-stained sections at a magnification of ×100. (C and D) H&E-stained and immunohistochemically stained sections at a magnification of ×400. The arrows indicate representative cells having ring-shaped nuclear morphology, and the arrowheads indicate representative neutrophils stained with RB6. (E and F) H&E-stained sections at a magnification of ×1,000. The arrows indicate PMN-like cells with ring-shaped nuclei. (G) Immunohistochemically stained sections at a magnification of ×1,000. The arrows indicate representative PMN-like cells that stained positive for MPO. The arrowheads indicate MNC-like ring cells that were negative for MPO staining or exhibited low levels of MPO staining.