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. 2004 Sep;72(9):5031–5040. doi: 10.1128/IAI.72.9.5031-5040.2004

FIG. 5.

FIG. 5.

Comparison of abilities of ALF to kill PspA-positive strains and their isogenic mutants making either truncated (secreted) PspA or no PspA. Strains JY53 and JY182 are pspA mutants of capsular type 2 strain D39. JY182 makes no PspA, and JY53 makes the N-terminal 43 kDa of D39 PspA. Strains JY1123 and JY1119 are pspA mutants of capsular type 3 strain WU2. JY1119 makes no PspA, and JY1123 makes the N-terminal 43 kDa of WU2 PspA. All strains were incubated with 3.1 μM ALF for 1 h at 37°C. Statistically significant effects of the mutations on killing by ALF are indicated: *, P ≤ 0.01; **, P ≤ 0.002. Each bar represent the mean log and standard error of 18 replicates performed in three independent experiments.