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Confocal micrographs demonstrating binding and internalization of M. fermentans and M. pneumoniae by HeLa cells. Following infection of HeLa cells with mycoplasmas for 0, 3, and 24 h, the cells were washed, fixed, and immunostained as described in Materials and Methods. Row A, HeLa cells infected with native M. fermentans; row B, HeLa cells infected with Pg- and uPA-treated M. fermentans; row C, HeLa cells infected with Pg- and uPA-treated M. pneumoniae.
