Changes in value of Walking Impairment Questionnaire (WIQ) score for each patient. One point represents one patient with peripheral arterial disease. Overlapped lines are expressed by bars on the line: for example, there are two patients whose pain score changed from 50 points to 75 points. The WIQ items of pain, distance, speed, and the total score of WIQ improved significantly (P <0.05) after administration of TJ-7. TJ-7, Tsumura Hachimi-jio-gan extract granules for medical use.