Table 2.
A comparison of ABI, SPP, and WIQ between baseline and after administration of TJ-7 for 6 months
| Baseline | After TJ-7 | Absolute change | P value | |
|---|---|---|---|---|
| ABI | 0.69 (0.48–0.81) | 0.73 (0.51–0.83) | 0.02 (−0.05–0.09) | 0.463 |
| SPP (mmHg) | ||||
| Dorsal | 52.5 (39.5–63.0) | 43.0 (35.0–50.0) | −9.0 (−16.0–2.50) | 0.011 |
| Plantar | 51.0 (37.5–57.0) | 46.0 (38.0–57.0) | −6.0 (−13.5–5.0) | 0.224 |
| WIQ | ||||
| Pain | 25.0 (0.0–50.0) | 75.0 (68.8–100.0) | 37.5 (25.0–75.0) | <0.001 |
| Distance | 31.0 (3.8–56.0) | 94.5 (27.0–100.0) | 30.0 (3.0–63.0) | 0.002 |
| Speed | 30.0 (9.8–48.8) | 50.0 (24.5–100.0) | 15.0 (2.3–43.3) | 0.003 |
| Climbing | 56.5 (23.0–91.0) | 88.0 (42.8–100.0) | 10.5 (−3.0–28.3) | 0.068 |
| Total score | 162.5 (32.0–250.0) | 308.0 (205.0–387.5) | 105.0 (53.8–166.0) | <0.001 |
Values are expressed as the median (interquartile range). ABI: ankle-brachial pressure index; SPP: skin perfusion pressure; WIQ: Walking Impairment Questionnaire; TJ-7: Tsumura Hachimi-jio-gan extract granules for medical use; Dorsal: dorsal side of the foot; Plantar: plantar side of the foot