Table 1.

Comparison of our patient to a study of reference in the literature²⁶ (36 patients, prior to vs 2–4 weeks after the first course of rituximab-based chemoimmunotherapy, in which 36% of patients were not on antivirals; presented values are median). Ferritin is one surrogate for HLH activity (Lin et al 2011)²⁷

	Treatment duration	VL (copies/mL)	Ferritin (μg/L)
Chellapandian et al26	2–4 week	114 200 to 225*	4260 to 1150
Our patient	2 week	100 000 to zero	46 500 to 2100

*In 22 patients (61%), VL dropped to <1000 copies/mL (n=14) or below the limits of detection (n=8).

HLH, haemophagocytic lymphohistiocytosis; VL, viral load.