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Serum antibody against HIV-1NL4-3 envelope glycoprotein gp120 in mice receiving multiple inoculations of SV(gp120) BALB/cJ mice were immunized at monthly intervals with 1 × 109 infectious units (IU) SV(gp120), IP. They were bled biweekly. Gp120-specific antibody reactivity was assayed by CELISA, as described in Methods and in reference #12. Specific binding of HIV-1 Env is shown here as specific A405nm, ± S.E.M.
