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. 2016 Dec 21;6:39404. doi: 10.1038/srep39404

Table 2. Methodological quality of case-control studies in our meta-analyses, based on the Newcastle–Ottawa Scale.

Study Selection (score) Comparability (score) Exposure (score)
Adequate definition of patient cases Representativeness of patients/cases Selection of controls Definition of controls Control for important factor or additional factor Ascertainment of exposure (blinding) Same method of ascertainment for participants Non-response ratea Total scoreb
Migita et al.12 1 1 0 1 0 0 1 1 5
Kim et al.13 1 1 0 1 0 0 1 1 5
Chen et al.14 1 1 1 1 1 0 1 1 7
Teixeira et al.15 1 1 1 1 0 0 1 1 6
Karra et al.16 1 1 0 1 0 0 1 1 5
Bao et al.17 1 1 1 1 2 0 1 1 8
Zhang et al.18 1 1 1 1 2 0 1 1 8
Lau et al.19 1 1 0 1 1 0 1 1 6

aOne point was awarded when there was no significant difference in the response rate between both groups based on the chi-squared test (P > 0.05).

bCalculated by adding up the points awarded for each item.