Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Dec 21;6:39491. doi: 10.1038/srep39491

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A) A heat map showing the relative abundances of the OGUs in P. acnes loci 1, 2, and 3 in acne patients and healthy individuals. Each column represents an OGU, ordered based on the genomic location of the OGUs. OGUs 101–200 in the pan-genome were plotted to show locus 1, flanking OGUs, and locus 2. The 74 OGUs from locus 3, which is a plasmid, are also shown. Each row represents an individual. Acne patients (n = 38) and healthy individuals (n = 34, including those with age over 55) were compared. Individuals within each group were clustered based on the average relative abundance of locus 2 OGUs. Ribotype composition and past and current acne treatments are indicated on the right. Multiple treatments are depicted by more than one color. (B) Fold changes in relative abundance of the OGUs in loci 1, 2, and 3 between acne patients and healthy individuals. Acne-associated OGUs had a fold change >1, while health-associated OGUs had a fold change <1. (C) Prevalence ratio of the OGUs in loci 1, 2, and 3 between acne patients and healthy individuals. The presence of an OGU in a sample is defined as an OGU with at least 1X coverage after normalization.