Table 4. Associations between DPP4a and no-reflow events, iMACCE, IHC, and in-hospital major bleeding events.
| Unadjusted | p Value | Model 1* | p Value | Model 2† | p | |
|---|---|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | ||||
| No reflow phenomenon | ||||||
| Q1 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| Q2 | 1.70 (0.61–4.79) | 0.3 | 1.71 (0.61–4.82) | 0.31 | 1.38 (0.41–4.63) | 0.61 |
| Q3 | 2.08 (0.76–5.67) | 0.12 | 2.16 (0.79–5.91) | 0.13 | 2.81 (0.89–8.85) | 0.08 |
| Q4 | 3.02 (1.16–7.83) | 0.02 | 3.16 (1.20–8.29) | 0.02 | 3.39 (1.08–10.61) | 0.04 |
| per 1 U/L | 1.05 (1.02–1.09) | <0.01 | 1.06 (1.02–1.09) | <0.01 | 1.07 (1.02–1.11) | <0.01 |
| iMACCE | ||||||
| Q1 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| Q2 | 1.00 (0.14–7.17) | 1.00 | 1.00 (0.14–7.28) | 1.00 | 0.88 (0.11–7.23) | 0.91 |
| Q3 | 0.50 (0.04–5.56) | 0.57 | 0.48 (0.04–5.38) | 0.55 | 0.50 (0.04–6.13) | 0.59 |
| Q4 | 0.50 (0.05–5.53) | 0.57 | 0.49 (0.04–5.58) | 0.56 | 0.45 (0.04–5.91) | 0.55 |
| per 1 U/L | 0.97 (0.88–1.07) | 0.52 | 0.97 (0.88–1.07) | 0.51 | 0.97 (0.88–1.07) | 0.57 |
| IHC | ||||||
| Q1 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| Q2 | 0.74 (0.40–1.38) | 0.35 | 0.78 (0.41–1.45) | 0.43 | 0.99 (0.47–2.09) | 0.98 |
| Q3 | 0.87 (0.48–1.60) | 0.66 | 0.92 (0.50–1.68) | 0.78 | 1.03 (0.48–2.18) | 0.95 |
| Q4 | 0.83 (0.45–1.52) | 0.54 | 0.95 (0.51–1.76) | 0.87 | 0.90(0.40–2.03) | 0.81 |
| per 1 U/L | 1.00 (0.98–1.03) | 0.86 | 1.01 (0.98–1.04) | 0.53 | 1.01 (0.98–1.04) | 0.40 |
| Major bleeding | ||||||
| Q1 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| Q2 | 0.56 (0.16–1.95) | 0.36 | 0.57 (0.17–2.00) | 0.38 | 0.61 (0.10–3.75) | 0.54 |
| Q3 | 0.71 (0.22–2.28) | 0.57 | 0.74 (0.23–2.39) | 0.62 | 1.04 (0.22–5.01) | 0.95 |
| Q4 | — | — | — | |||
| per 1 U/L | 0.92 (0.86–0.98) | 0.01 | 0.92 (0.86–0.98) | 0.01 | 0.90 (0.82–0.98) | 0.02 |
IHC, in-hospital complications; iMACCE, in-hospital major adverse cardiac or cerebrovascular events; DPP4a, plasma dipeptidyl peptidase-4 activity; OR, odds ratio; CI, confidence interval.
*Adjusted for age and sex.
†Adjusted for age, sex, BMI, creatinine, GGT, total cholesterol, fibrinogen, peak CK-MB, pro-BNP, fasting plasma glucose, hypertension, previous MI, smoking status, ACEI/ARB use, and β-blocker use.