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. 2016 Dec 21;6:39520. doi: 10.1038/srep39520

Figure 5. HCV induces M2 activation in monocytes and macrophages.

Figure 5

(A) Human monocytic cells (THP1) were inoculated with supernatant from JFH1/genotype 2-infected Huh7.5 cells or mock-infected Huh7.5 cells and macrophage polarization was examined using gene expression analysis after 6 days. (B,C) Primary human monocytes were differentiated to M1 or M2 macrophages and were inoculated with supernatant from JFH1/genotype 2-infected Huh7.5 cells or mock-infected Huh7.5 cells and macrophage polarization markers were examined using gene expression (B) and cytokine (C) analysis after 6 days.