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. 2016 Dec 21;6:39462. doi: 10.1038/srep39462

Table 2. In vitro growth inhibitory activity (expressed as IC50) of the human and chimeric AMA1-specific antibodies against P. falciparum strains 3D7A, HB3 and FCR3.

Parasite strain 3D7A HB3 FCR3
Antibody
  IC50 (95% Confidence Interval)
humAbAMA1 (N.b.) 35 (33–37) μg/ml 126 (112–141) μg/ml 196 (159–239) μg/ml
humAbAMA1 (HEK293-6E) 35 (34–37) μg/ml ND ND
4G2 (N.b.) 105 (99–111) μg/ml 396 (362–433) μg/ml 817 (674–990) μg/ml
1F9 (N.b.) 292 (250–342) μg/ml >1750 μg/ml 1438 (1233–1676) μg/ml

ND: Not determined; N.b.: Nicotiana benthamiana.