Table 2.
Coefficients of variation (mean and range %) and Bland–Altman limits of agreement (BALA %) for DCE-MRI parameters obtained with the Tofts model (TM) and the shutter-speed model (SSM) in the test–retest study (n = 10)
| Parameter | Model | Liver | HCC |
|---|---|---|---|
| ART | TM | ||
| CV (%) | 63.3 (4.9–137.2) | 31.4 (0.0–138.6) | |
| BALA (%) | −267.6, 185.1 | −152.9, 155.6 | |
| SSM | |||
| CV (%) | 66.5 (8.5–141.4) | 54.9 (0.0–141.4) | |
| BALA (%) | −273.4, 185.2 | −229.5, 198.1 | |
| Ktrans | TM | ||
| CV (%) | 47.1 (0.0–112.9) | 28.9 (0.0–82.9) | |
| BALA (%) | −136.1, 174.8 | −105.7, 134.8 | |
| SSM | |||
| CV (%) | 46.5 (0.1–113.5) | 25.1 (0.0–94.9) | |
| BALA (%) | −144.4, 175.2 | −119.2, 126.5 | |
| ve | TM | ||
| CV (%) | 37.9 (0.4–79.5) | 36.3 (0.0–89.4) | |
| BALA (%) | −86.3, 139.9 | −98.0, 158.9 | |
| SSM | |||
| CV (%) | 39.4 (1.5–74.1) | 50.8 (2.0–93.1) | |
| BALA (%) | −89.1, 143.6 | −106.2, 191.9 | |
| kep | TM | ||
| CV (%) | 34.4 (3.2–87.9) | 44.1 (3.3–82.9) | |
| BALA (%) | −128.9, 124.3 | −160.3, 123.4 | |
| SSM | |||
| CV (%) | 32.2 (2.2–88.2) | 38.2 (2.2–65.2) | |
| BALA (%) | −130.6, 117.5 | −132.6, 47.3 | |
| τi | SSM | ||
| CV (%) | 14.7 (0.0–55.9) | 42.6 (0.0 − 130.5) | |
| BALA (%) | −69.4, 81.6 | −206.1, 161.5 |
ART arterial fraction (%), Ktrans CA transfer rate constant from the blood plasma into the extravascular and extracellular space (min−1), ve extravascular and extracellular space volume fraction, kep CA intravasation rate constant (min−1), τi: mean intracellular water molecule lifetime (s)