Figure 1.

Deletion of the RAD1 and RAD10 genes, but not of other NER genes, enhances the H₂O₂ sensitivity of the apn2Δ strain. (A) Effect of deletions of NER genes on the H₂O₂ sensitivity of the apn1Δ strain. (○) Wild type; (▪) apn1Δ; (- -♦- -) rad1Δ; (- -⋄- -) rad2Δ; (----▴----) rad4Δ; (▵) rad10Δ; (▿) rad14Δ; (----▿----) apn1Δ rad1Δ; (□) apn1Δ rad2Δ; (▾) apn1Δ rad4Δ; (▴) apn1Δ rad10Δ; (•) apn1Δ rad14Δ. Because of their similar H₂0₂ sensitivities, the wild-type strain and some of the single mutant strains cannot be distinguished from one another. (B) Effect of deletion of NER genes on the H₂O₂ sensitivity of the apn2Δ strain. Symbols as in A except that apn2Δ instead of apn1Δ is combined with the radΔ mutations. Only the sensitivity of the apn2Δ rad1Δ (----▿----) and apn2Δ rad10Δ (▴) is greatly enhanced. (C) Effect of deletions of NER genes on the H₂O₂ sensitivity of the apn1Δ apn2Δ strain. (○) Wild type; (- -♦- -) rad1Δ; (- -⋄- -) rad2Δ; (----▴----) rad4Δ; (▵) rad10Δ; (▿) rad14Δ; (▪) apn1Δ apn2Δ; (□) apn1Δ apn2Δ rad2Δ; (▾) apn1Δ apn2Δ rad4Δ; (•) apn1Δ apn2Δ rad14Δ.