Table 1.
Relationship between various parameters at the time of liver transplantation and the incidence of hepatic steatosis on 10-year post-liver transplantation biopsy
| All subjects n = 72 | No HS n = 48 | HS n = 24 | P1 | |
| Age (yr) | 35 ± 19 | 32 ± 21 | 42 ± 12 | 0.04 |
| Gender (female) | 52% | 60% | 71% | NS |
| Disease | ||||
| Acute hepatic failure | 24% | 27% | 17% | NS |
| Primary biliary cirrhosis | 25% | 25% | 25% | NS |
| HBV-related cirrhosis | 8% | 6% | 12% | NS |
| Autoimmune cirrhosis | 7% | 6% | 8% | NS |
| Biliary atresia | 5% | 8% | 0% | NS |
| HCV-related cirrhosis | 12% | 6% | 25% | NS |
| Metabolic disease (Wilson disease) | 1% | 2% | 0% | NS |
| Alcohol related cirrhosis | 1% | 2% | 0% | NS |
| Primary sclerosing cholangitis | 4% | 4% | 4% | NS |
| Cryptogenic cirrhosis | 2% | 4% | 0% | NS |
| Hepatocellular carcinoma | 8% | 8% | 8% | NS |
| ABO compatible | 97% | 96% | 100% | NS |
| Donor age (years) | 27 ± 11 | 27 ± 12 | 27 ± 10 | NS |
| Donor gender (female) | 41% | 42% | 39% | NS |
| Urgency | 25% | 27% | 21% | NS |
| Cold ischemic time (min) | 410 ± 212 | 406 ± 215 | 429 ± 214 | NS |
| Reperfusion biopsy2 | ||||
| Steatosis (≥ 10%) | 18% | 15% | 22% | NS |
| % of steatosis | 24 ± 15 | 31 ± 16 | 16 ± 8 | NS |
| Reperfusion lesions | ||||
| Mild | 26% | 31% | 17% | NS |
| Moderate to severe | 60% | 50% | 79% | NS |
Continuous data are represented as mean ± SD, and categorical data as percentage.
1
Comparison between HS and No HS;
2
Reperfusion biopsy not done in 10 cases (9 in Non HS group and 1 in HS group). HS: Hepatic steatosis; NS: Not significant; HCV: Hepatitis C virus.