Table 4.
Minimal inhibitory concentrations for the tested isolates
Antibiotics | Isolate | pH 5_R2_1_I_A Methylobacterium tardum |
pH 5_R2_1_I_B Bradyrhizobium erythrophlei |
pH 5_R2_1_II_A Cupriavidus metallidurans |
pH 5_R2_2_I_B Brevibacterium halotolerans |
pH 5_R2_2_I_A Bacillus subtilis |
pH 5_R2_2_II_A Bacillus subtilis |
pH 5_R2_5_I_B Bacillus licheniformis |
pH 7_R2F_2_A Bacillus pumilus |
pH 7_R2F_2_C Bacillus aerophilus |
pH 9_R2_3_II_A Micrococcus yunnanensis |
pH 9_R2_5_I_B Bacillus pumilus |
pH 9_R2_5_II_B Bacillus clausii |
pH 9_R2_5_I_C Bacillus safensis |
r2a5R0,2 Bacillus licheniformis |
r2a5R0,5 Bacillus licheniformis |
ms2R0,5 Bacillus thermoamylovorans |
pH7_anox_R2 Bacillus licheniformis |
pH9_R2IIA Paenibacillus campinasensis |
pH9_R2IID Bacillus timonensis |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Max. concentration: 256 μg/ml | ||||||||||||||||||||
Amoxicillin/clavulanic acid | 2 | 256 a | 1.5 | 2 | 3 | 0.5 | 7 | 3 | 0.25 | 0.75 | 2 | 0.19 | 3 | 16 | 12 | 0.19 | 3 | 256 a | 2 | |
Cefotaxime | 12 | 256 a | 1 | 2 | 8 | 16 | 64 | 256 a | 128 | 0.75 | 16 | 32 | 256 a | 24 | 32 | 32 | 256 a | 12 | 32 | |
Ceftriaxone | 1.5 | 256 a | 0.5 | 1.5 | 0.38 | 12 | 256 a | 32 | 16 | 0.19 | 4 | 12 | 24 | 24 | 12 | 8 | 64 | 12 | 48 | |
Linezolid | 256 a | 256 a | 256 a | 1 | 1 | 0.75 | 1 | 2 | 1.5 | 1 | 0.75 | 1 | 2 | 1.5 | 1 | 1 | 2 | 6 | 1 | |
Penicillin G | 3 | 256 a | 3 | 8 | 0.75 | 0.5 | 256 a | 0.38 | 0.064 | 0.094 | 256 a | 24 | 0.25 | 24 | 6 | 4 | 0.75 | 24 | 1 | |
Ampicillin | 256 a | 256 a | 1.5 | 2 | 3 | 16 | 256 a | 2 | 0.25 | 0.5 | 1.5 | 24 | 2 | 24 | 8 | 2 | 3 | 256 a | 2 | |
Colistin | 256* | 256a | 24 | 32 | 32 | 64 | 64 | 48 | 12 | 2 | 32 | 3 | 24 | 32 | 32 | 64 | 24 | 48 | 16 | |
Clarithromycin | 2 | 256a | 2 | 0.094 | 0.064 | 0.064 | 0.38 | 0.125 | 0.064 | 4 | 0.064 | 256a | 0.5 | 0.064 | 256a | 256a | 0.032 | 256a | 0.032 | |
Clindamycin | 256* | 256a | 256a | 0.5 | 0.75 | 0.5 | 12 | 3 | 2 | 0.25 | 24 | 256a | 4 | 4 | 8 | 1 | 4 | 256a | 2 | |
Doxycycline | 1.5 | 256a | 0.064 | 0.047 | 0.094 | 0.19 | 0.25 | 0.19 | 0.094 | 0.25 | 0.064 | 0.25 | 0.125 | 0.125 | 0.25 | 0.75 | 0.38 | 0.125 | 0.19 | |
Gentamicin | 8 | 96 | 32 | 0.094 | 0.094 | 0.75 | 0.38 | 0.125 | 0.064 | 0.38 | 0.5 | 0.064 | 0.094 | 0.19 | 0.75 | 0.125 | 0.064 | 0.75 | 0.064 | |
Vancomycin | 256a | 256a | 0.75 | 256a | 1 | 2 | 3 | 1.5 | 1 | 0.19 | 2 | 0.75 | 0.75 | 1 | 8 | 2 | 2 | 4 | 1.5 | |
Max. concentration: 32 μg/ml | ||||||||||||||||||||
Ciprofloxacin | 6 | 32 a | 0.016 | 0.047 | 0.064 | 0.064 | 0.125 | 0.19 | 0.094 | 0.75 | 0.032 | 0.75 | 0.094 | 0.094 | 0.047 | 0.19 | 0.125 | 0.125 | 0.125 | |
Levofloxacin | 3 | 32 a | 0.047 | 0.094 | 0.125 | 0.094 | 0.19 | 0.25 | 0.125 | 1.5 | 0.094 | 2 | 0.125 | 0.094 | 0.064 | 0.38 | 0.125 | 0.094 | 0.094 | |
Meropenem | 32 a | 32 a | 0.125 | 0.064 | 0.19 | 0.094 | 0.19 | 0.25 | 0.094 | 0.47 | 0.094 | 1 | 0.25 | 19 | 19 | 0.38 | 0.38 | 3 | 0.38 | |
Moxifloxacin | 0.25 | 32 a | 0.023 | 0.016 | 0.047 | 0.023 | 0.032 | 0.640 | 0.016 | 0.38 | 0.008 | 0.5 | 0.023 | 16 | 0.012 | 0.032 | 0.025 | 0.047 | 0.023 | |
Trimethoprim/sulfamethoxazole | 32a | 32a | 0.064 | 0.125 | 0.19 | 0.19 | 0.19 | 0.004 | 0.004 | 0.5 | 0.032 | 0.047 | 0.094 | 0.032 | 0.032 | 0.094 | 0.006 | 0.75 | 0.004 |
Italic underlined: sensitive according to non-species related breakpoints of EUCAST; Bold: resistant according to non-species related breakpoints of EUCAST; Slow growing M. tardum and B. erythrophlei were tested on R2A medium with 2 days incubation time since they did not grow at all on MH medium
aGrew at the tested maximum concentration of the respective antibiotic; concentrations given in: μg/ml