Table 4.
Bivariate and multivariate Cox-regression analysis of socio-demographic and baseline clinical characteristics of the cohort studied in Fiche Hospital, North Shoa during September 2006 to 2013, (N = 489 patients)
| Covariates | Number at risk | Number of deaths | Crude HR (95% CI) | Adjusted HR (95% CI) |
|---|---|---|---|---|
| Educational status | ||||
| No education | 138 | 36 | 1.86 (0.73, 4.76) | 1.35 (0.50, 3.6) |
| Primary | 164 | 26 | 1.60 (0.63, 4.10) | 2.05 (0.78, 5.36) |
| Secondary | 152 | 23 | 0.61 (0.22, 1.71) | 0.92 (0.31, 2.74) |
| Tertiary | 35 | 2 | 1 | |
| Nutritional status | ||||
| Malnourished | 163 | 41 | 7.58 (4.63, 12.39) | 5.40 (3.03, 9.58)** |
| Non-malnourished | 326 | 46 | 1 | |
| Functional status | ||||
| Working | 265 | 8 | 1 | |
| Ambulatory | 197 | 69 | 4.91 (2.91, 8.26) | 3.84 (2.19, 6.74)** |
| Bedridden | 27 | 10 | 6.86 (3.26, 14.44) | 4.78 (2.14, 10.65)** |
| WHO clinical stage | ||||
| Stage I and II | 245 | 6 | 1 | |
| Stage III | 220 | 71 | 3.1 (1.89, 5.07) | 2.21 (1.16, 4.21)* |
| Stage IV | 24 | 10 | 5.93 (2.89, 12.17) | 4.05 (1.50, 10.97)** |
| TB history | ||||
| Yes | 148 | 47 | 1.99 (1.31, 3.05) | 0.95 (0.58, 1.55) |
| No | 341 | 40 | 1 | |
| CD4 count (cells/μl) | ||||
| ≤200 | 335 | 260 | 3.44 (1.83, 6.48) | 2.95 (1.48, 5.88)* |
| >200 | 154 | 142 | 1 | |
| Hemoglobin level (n = 467) | ||||
| <10 g/dl | 64 | 18 | 1.80 (1.06, 3.04) | 0.82(0.45, 1.51) |
| ≥10 g/dl | 403 | 62 | 1 | |
| Previous OIs | ||||
| None | 304 | 15 | 1 | |
| One | 68 | 18 | 1.80 (0.99, 3.52) | 1.31 (0.69, 2.5) |
| 2+ | 117 | 54 | 3.24 (2.05, 5.13) | 2.30 (1.11, 4.75)* |
| HIV related counseling | ||||
| Yes | 141 | 6 | 1 | |
| No | 348 | 81 | 3.85 (2.44, 6.08) | 0.57 (0.26, 1.24) |
1.00 = Reference * P value <0.05, ** P value ≤0.001