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. 2016 Sep 20;44(20):9784–9802. doi: 10.1093/nar/gkw840

Figure 4.

Figure 4.

Histone H3K4me3 occupancy is affected in the Pou5f1 and Klf1 genes in the first generation after treatment and remains detectable in the third generation. The schematic presentation of H3K4me3 marks in the (A) Pouf5f1 and (B) Klf1 gene. These genes have altered H3K4me3 peaks in the F1 generation and the changes are also detectable in the F3 generation. In the Pouf5f1 gene, the H3K4me3 occupancy is increased in F1 and the change is still present in F3. In the Klf1 gene, the H3K4me3 occupancy is decreased in F1 and the change is still present in F3.