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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Transplantation. 2016 Dec;100(12):2630–2639. doi: 10.1097/TP.0000000000001465

Figure 2. Decreasing the dose of radiation ameliorates radiation-induced pathology, but doesn't support xenoGVHD.

Figure 2

To determine the effect of radiation dose on xeno-GVHD, NSG mice were treated with either 50 or 200 cGray and administered PBS only or 30×106 PBMNC. Disease severity was measured by weight loss (A), clinical score (B) and survival (C). * denotes days when average weight or clinical score for 200rad + 30×106 PBMNC had p<0.05 compared to 200rad only. # denotes days when average weight or clinical score for 50rad only had p<0.05 compared to 200rad only. n= 5 mice per group.