Table 4.

Estimated HR for Incident Prehypertension/Hypertension by VMS Categories, 1353 Women Normotensive at Baseline

Unadjusted	HR (95% CI)	p	No. observations/No. events
None	Reference	0.0001	6385/620
1–5 days	1.22 (1.01, 1.48)
6+ days	1.62 (1.30, 2.03)
Model 1
None	Reference	0.0024	6385/620
1–5 days	1.20 (0.98, 1.46)
6+ days	1.50 (1.19, 1.89)
Model 2
None	Reference	0.0443	6257/589
1–5 days	1.08 (0.87, 1.33)
6+ days	1.39 (1.08, 1.79)

VMS was assessed concurrently with each visit and VMS was treated as a time-varying covariate. Unadjusted: model includes only current VMS frequency and time since baseline; Model 1: adjusted for baseline age and site; Model 2: variables including in Model 1, race, education level, current menopausal status, baseline parity, baseline alcohol consumption, baseline physical activity, current smoking status, current anxiety score, current BMI; Prehypertension (SBP 120–139 mmHg or DBP 80–89 mmHg); hypertension (use of an antihypertensive agent or SBP ≥140 mmHg or DBP ≥90 mmHg) per JNC VII.

HR, hazard ratio.